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Vaccines and Treatments

October 29th, 2020

How do vaccines and treatments work? What is the difference between a vaccine and a treatment? Is a vaccine or a treatment better? Where do new vaccines and treatments come from? Join BioBus and our special guests from Regeneron, Dr. Lisa A. Purcell (Clinical Sciences, Immunology and Inflammation and Scientific Director, Secondary Education Programs), Dr. Kurt H. Edelmann (Senior Staff Scientist, Infectious Diseases), Dr. Sokol Haxhinasto (Senior Staff Scientist, Infectious Diseases), and Dr. Anna Zumsteg (Senior Staff Scientist, Infectious Diseases) as we answer your questions about vaccines and treatment!

Guest Speakers

Dr. Lisa A. Purcell, PhD

Microbiologist and Virologist

Lisa Purcell joined Regeneron in 2008 and is a Clinical Scientist in Immunology and Inflammation. She received her PhD from McGill University and completed her Postdoctoral Training at Columbia University. Dr. Purcell’s current work focuses on the clinical development of therapies within the immunology and infectious disease therapeutic areas, including those for SARS-CoV-2/COVID-19. She has also developed therapies for pathogens using Regeneron’s novel technologies. Dr. Purcell was the scientific director of Regeneron’s science education efforts including the Regeneron Science Talent Search, research mentorship efforts, the International and Westchester Science and Engineering Fair and STEM teacher programs. She is currently the Vice President of Vir Biotechnology.

Dr. Kurt H. Edelmann, PhD

Senior Staff Scientist at Regeneron

Kurt Edelman is an infectious disease scientist specializing in immunology and virology with 14 years of industry experience at two leading biotech companies (Amgen & Regeneron).

Dr. Sokol Haxhinasto, PhD

Associate Director of Immunology at Regeneron

Sokol is a Lab Head in the Immunology and Inflammation group with a broad interest in cellular and molecular mechanisms that ensure optimal immune responses in health and understanding of their dysregulation in autoimmune disease. His work focuses on preclinical modeling of human disease, deep profiling of the immunological players and disease mechanisms with the goal of identifying and validating novel therapeutic options to address unmet medical needs.

Dr. Anna Zumsteg, PhD

Microbiologist

Anna Zumsteg has been with Regeneron since 2014 and was a Senior Staff Scientist in the Infectious Diseases therapeutic focus area. During her PhD at Stanford University and Postdoctoral Training at the Max Planck Institute for Infection Biology, she explored concepts in host-pathogen interactions critical for disease. At Regeneron, her work focused on applying that understanding to design new approaches to more effectively treat bacterial infections. She is currently the Director at Vir Biotechnology.

Question Index

1. 8:34 - How did vaccines get discovered? 2. 11:34 - How do vaccines work? 3. 18:18 - Why are there so many vaccines? 4. 19:27 - How do vaccines and treatments keep us safe from pathogens? 5. 21:24 - Can smallpox come back? 6. 22:23 - Can there be vaccines for plants? 7. 23:36 - How does a virus end up starting a pandemic? 8. 25:26 - How did COVID-19 actually start? 9. 28:15 - How long does a person have COVID-19 for? 10. 31:34 - Where do vaccines and treatments come from? 11. 32:46 - How do you know when a vaccine is good enough to be released/used? 12. 35:32 - How many tests have to be done before a vaccine is ready? 13. 41:17 - Are we any closer to making a vaccine for COVID-19? When might we find/make one? 14. 44:18 - Is it possible for vaccines to give people the disease that they are actually trying to prevent? 15. 46:28 - Can we go to school everyday once the vaccine is made? 16. 48:25 - How has the process of creating vaccines changed over time? 17. 50:35 - What's the difference between a treatment and vaccine? 18. 53:46 - How do we figure out how to treat different kinds of people? Should all people be treated in the same way? Or should they be treated differently? 19. 55:30 - Once there's a vaccine, will we still need to wear masks and remain in social distance?
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